A supervised oral challenge was performed with paracetamol an initial dose of 100 mg was tolerated, but following a 900 mg dose he developed a widespread urticarial rash.Ī female aged 19 years had four episodes of anaphylaxis characterised by persistent coughing, breathlessness, facial angioedema, urticaria and on one occasion collapse. There were no other triggers to the reactions, he had previously tolerated paracetamol and he subsequently tolerated ibuprofen. He was successfully treated with antihistamines on both occasions. The onset of symptoms occurred two hours after paracetamol ingestion on the first occasion and within 10 minutes on the second occasion.
A male aged 24 years developed immediate systemic hypersensitivity reactions characterised by urticaria, diarrhoea, diaphoresis and palpitations on two occasions after ingesting 1 g of paracetamol for a headache.
0 kommentar(er)
